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The Spinal Cord From Gestational Week To The 4th Postnatal Month Atlas Of Human

Jese Leos
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Published in The Spinal Cord From Gestational Week 4 To The 4th Postnatal Month (Atlas Of Human Central Nervous System Development 1)
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If you've ever wondered about the development of the human spinal cord from gestational week until the fourth postnatal month, you've come to the right place. In this article, we will take you on a fascinating journey through the different stages of spinal cord development in humans, highlighting key milestones that shape our central nervous system.

Gestational Week 4-8: The Formation Begins

During the fourth week of gestation, the embryonic neural tube undergoes a process known as neurulation. This crucial step sets the groundwork for the formation of the spinal cord. The neural tube differentiates into three primary vesicles, namely the prosencephalon, mesencephalon, and rhombencephalon. It is from the latter that the spinal cord will develop.

By the eighth week, the neural tube's caudal end closes, marking the completion of primary neurulation. The open neural folds further differentiate into ventral and dorsal aspects, allowing the neural tube to assume its characteristic shape as the precursor to the spinal cord.

The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month (Atlas of Human Central Nervous System Development 1)
The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month (Atlas of Human Central Nervous System Development Book 1)
by Karen Kruse Thomas(1st Edition, Kindle Edition)

5 out of 5

Language : English
File size : 41253 KB
Screen Reader : Supported
Print length : 256 pages
X-Ray for textbooks : Enabled

Gestational Week 9-12: Differentiation and Growth

As the embryo continues to develop, major changes occur in the spinal cord during gestational weeks 9-12. The neural tube differentiates into specialized regions, including the cervical, thoracic, lumbar, and sacral enlargements. These enlargements correspond to the segments of the spinal cord that will innervate different parts of the body.

During this period, neuroblasts - the precursors of neurons - start migrating from the ventricular zone toward the mantle layer. Axons begin to grow, forming a primitive network within the spinal cord. Meanwhile, the formation of glial cells, essential for providing support to the developing nervous system, also begins.

Gestational Week 13-20: Patterning and Refinement

As the second trimester begins, the spinal cord's development enters a phase of fine-tuning and refinement. Axons continue to grow, forming distinct tracts that will carry neural signals throughout the body.

The dorsal and ventral regions of the spinal cord become further differentiated, and motor neurons start to develop in the ventral horn. At this stage, the fetus can make spontaneous movements, which are essential for the proper maturation of the motor system.

Gestational Week 21-28: Further Maturation

By the third trimester, the neurodevelopmental processes in the spinal cord intensify. The structures within the spinal cord become more defined, and the neuronal connections become stronger and more intricate.

During this period, the interneurons, which play crucial roles in coordinating sensory and motor signals, become more functionally integrated within the spinal cord circuitry. There is also increased myelination, which enhances the speed and efficiency of nerve impulse conduction.

Postnatal Month 1-4: The First Months

After birth, the development of the spinal cord continues during the first few months of life. The already established neuronal connections are further refined as the central nervous system adapts to the external environment.

During this period, the baby's motor skills undergo significant development. Infants start acquiring voluntary control over their movements, such as reaching and grasping objects. These motor milestones are closely linked to the maturation of the spinal cord and the brain's motor areas.

The journey of spinal cord development from gestational week until the fourth postnatal month is a remarkable and complex process. Through a series of intricate steps, the spinal cord transforms from a simple tube into a sophisticated structure capable of transmitting and coordinating signals essential for our movement and sensory experiences.

Understanding the timeline of spinal cord development provides valuable insights into the complexities of the human nervous system. As we continue to uncover the mysteries of neurodevelopment, we unlock the potential to unravel various neurological disorders and develop innovative treatments for a range of conditions.

The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month (Atlas of Human Central Nervous System Development 1)
The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month (Atlas of Human Central Nervous System Development Book 1)
by Karen Kruse Thomas(1st Edition, Kindle Edition)

5 out of 5

Language : English
File size : 41253 KB
Screen Reader : Supported
Print length : 256 pages
X-Ray for textbooks : Enabled

This first volume in the Atlas of Human Central Nervous System Development series sets the stage with complete coverage of the spinal cord from gestational week 4 to the 4th postnatal month. 3D color images provide a holistic view of the structural changes during spinal cord morphogenesis.
This landmark first volume:

  • Provides quantitative summaries of several ontogenetic trends
  • Features all the stages of spinal cord development
  • Offers fresh insights into the steps involved in the morphogenesis of the mature spinal cord
  • Shows the human spinal cord at its most primitive stage, when consisting mainly of neuroepithelial stem cells

This atlas is also available as part of the complete five volume
series.

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